Table 1:
Quantitative scoring of histological findings
| Evaluation items | Implantation period |
||
|---|---|---|---|
| 12 months (n = 3) | 24 months (n = 2) | 36 months (n = 2) | |
| Regenerated wall, maturity | |||
| Tissue regeneration | |||
| Granulation tissue | 1, 0, 1 | 0, 0 | 0, 0 |
| Smooth muscle cells | 1, 2, 2 | 3, 3 | 2, 2 |
| Collagen fibres | 4, 2, 2 | 2, 3 | 2, 2 |
| Endothelial cells (luminal surface) | 3, 3, 3 | 3, 3 | 3, 3 |
| Elastic fibres | 0, 2, 0 | 1, 2 | 1, 1 |
| Bridge formation | 1, 3, 4 | 4, 3 | 4, 4 |
| Inflammatory cells infiltration | |||
| Neutrophils | 0, 0, 0 | 0, 0 | 0, 0 |
| Lymphocytes | 0, 1, 1 | 1, 1 | 1, 0 |
| Plasma cells | 0, 0, 0 | 0, 0 | 0, 0 |
| Macrophages/giant cells | 1, 1, 3 | 1, 1 | 1, 0 |
| Material condition (SHF) | |||
| Gelatine remaining | 2, 1, 1 | 0, 0 | 0, 0 |
| Calcium deposition | 0, 0, 0 | 0, 0 | 0, 0 |
Grading: 0 none; 1 very slight; 2 mild; 3 moderate; 4 marked (Supplementary Material, Table S1). Raw data are shown as, for example, ‘2, 1’, which means that the scores were 2 and 1 in the 2 animals. SHF: synthetic hybrid fabric.