Table 2. Hemochromatosis probands with HFE p.C282Y homozygosity and cirrhosisa.
Characteristics | Abdominal pain (n = 5) | No abdominal pain (n = 17) | Value of p |
---|---|---|---|
Male, % (n) | 60.0 (3) | 94.1 (16) | 0.0239 |
Mean age at diagnosis, y, ± 1 SD | 50 ± 9 | 59 ± 7 | 0.0835 |
Diabetes, % (n)b | 40.0 (2) | 17.6 (3) | 0.5431 |
Heavy alcohol consumption, % (n) | 20.0 (1) | 23.5 (4) | 1.0000 |
Hepatomegaly, % (n) | 40.0 (2) | 47.1 (8) | 1.0000 |
Splenomegaly, % (n) | 20.0 (1) | 11.8 (2) | 1.0000 |
NAFLD, % (n) | 20.0 (1) | 29.4 (5) | 1.0000 |
Chronic viral hepatitis, % (n) | 0 (0) | 23.5 (4) | 0.5304 |
Ascites, % (n) | 0 (0) | 5.9 (1) | 1.0000 |
Hepatic sarcoidosis, % (n) | 20.0 (1) | 0 (0) | 0.2273 |
a Abbreviations: SD, standard deviation; NAFLD, non-alcoholic fatty liver disease.