Table 3.

Craniofacial and velopharyngeal features of the patients with 22q11.2 deletions.

	Case 1	Case 2	Case 3	Case 4	Case 5	Case 6	Case 7	Case 8	Case 9	Case 10	Case 11	Case 12	Case 13	Case 14	Case 15	Case 16
Deletion regions	A	A	A	A	A-D	A-D	A-D	A-D	A-D	A-D	A-D	C-D	D-E	D-E	D-E	E-F
Hypertelorism							+	+						+
Frontal Bossing			+		+
Low set ears								+
Micrognathia				+	+
Cleft palate/VPI		S			S	S		V
Small head circumference at birth <5th centile		+									+
Small head circumference at 28 months <5th centile											+
High palate arch				+			+
Ear canal atresia														+
Periauricular tag				+										+
Brachycephalic														+
Retrognathia			+
Malocclusion			+
Glottic web									+			+
Upslanting palpebral fissure																+
Dysmorphic facies						+
Prominent nasal bridge														+
Microtia				+
Almond shaped eyes
Thin upper lip
Smooth philtrum

Notes: S, submucous cleft palate; VPI/V, velopharyngeal insufficiency.