ISRCTN26088319.

Methods	RCT (UK, Australia, New Zealand)
Participants	Participants with MDS, transfusion dependent, life expectancy > 6 months
Interventions	Liberal protocol: to maintain haemoglobin concentration Restrictive protocol: to maintain haemoglobin level between 8.5 g/dL and 10 g/dL
Outcomes	Percentage of compliance of pre‐transfusion haemoglobin levels with achievement of at least 2 g/dL difference between liberal and restrictive transfusion
Notes	Trial registration (prospective): ISRCTN26088319