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. 2021 Dec 21;2021(12):CD002042. doi: 10.1002/14651858.CD002042.pub5

NCT02099669.

Methods RCT (feasibility) (Canada)
Participants All participants with MDS ≥ 18 years of age, transfusion dependent: at least 1 transfusion per month in the last 8 weeks, haemoglobin < 10 g/dL
Interventions Liberal transfusion strategy: to maintain Hb between 11 g/dL and 12 g/dL
Restrictive transfusion strategy: to maintain Hb between 8.5 g/dL and 10 g/dL
Outcomes Percentage compliance
Notes Trial registration (prospective): NCT02099669

Abbreviations

Hb: haemoglobin concentration
MDS: myelodysplastic syndrome
RCT: randomised controlled trial