NIHR 130875.
Study name | The impact of REstrictive versus LIberal Transfusion strategy on cardiac injury and death in patients undergoing surgery for Hip Fracture (RESULT‐Hip) |
Methods | RCT |
Participants | Adults aged 60 years or older with hip fracture who become anaemic (< Hb 9.0 g/dL) during the 7 days following surgery Estimated enrolment: 1964 |
Interventions | Liberal group: transfusion threshold of Hb 9.0 g/dL (target Hb 9.0 g/dL to 11.0 g/dL) for duration of acute hospital stay Restrictive group: transfusion threshold of Hb 7.5 g/dL (target Hb 7.5 g/dL to 9.0 g/dL) for duration of acute hospital stay |
Outcomes | Primary outcome: death or MACE within 30 days of surgery. MACE will be defined as any combination of the following: death, myocardial Infarction, new arrhythmia, cardiac or respiratory arrest, cardiogenic pulmonary oedema |
Starting date | 2022 |
Contact information | Michael Gillies; michael.gillies@ed.ac.uk |
Notes | Funding: National Institute for Health Research (NIHR) ‐ Health Technology Assessment (UK) |