Table 4.

Multivariable Associations With Death and/or MI and MACE, According to the Presence of MI in the Entire Cohort and in Patients Without Ischemia on Stress CMR

	Death and/or MI		MACE			Death and/or MI		MACE
	HR (95% CI)	p Value	HR (95% CI)	p Value		HR (95% CI)	p Value	HR (95% CI)	p Value
Entire cohort
MI vs. no MI	1.69 (1.32–2.15)	<0.001	1.78 (1.46–2.16)	<0.001	UMI vs. RMI	0.84 (0.61–1.17)	0.307	0.86 (0.67–1.11)	0.255
Age, per 5 yrs	1.19 (1.13–1.26)	<0.001	1.12 (1.07–1.17)	<0.001	Age, per 5 yrs	1.10 (1.02–1.83)	0.019	1.03 (0.97–1.10)	0.302
Diabetes	1.45 (1.15–1.83)	0.002	1.38 (1.15–1.67)	<0.001	Diabetes	1.31 (0.93–1.83)	0.122	1.17 (0.89–1.53)	0.253
Smoking	1.38 (1.09–1.75)	0.007	1.32 (1.09–1.59)	0.004	Smoking	1.39 (1.00–1.94)	0.052	1.35 (1.04–1.75)	0.027
LVEF, per 5%	0.92 (0.89–0.96)	<0.001	0.91 (0.89–0.94)	<0.001	LVEF, per 5%	0.92 (0.88–0.97)	0.002	0.93 (0.89–0.96)	<0.001
Ischemia	1.30 (0.99–1.70)	0.062	1.66 (1.35–2.05)	<0.001	Ischemia	1.30 (0.92–1.84)	0.131	1.53 (1.17–1.99)	0.002
No ischemia on stress CMR
MI vs. no MI	1.69 (1.28–2.22)	<0.001	1.89 (1.51–2.36)	<0.001	UMI vs. RMI	0.83 (0.53–1.29)	0.409	0.94 (0.67–1.33)	0.738
Age, per 5 yrs	1.24 (1.16–1.32)	<0.001	1.16 (1.10–1.22)	<0.001	Age, per 5 yrs	1.14 (1.03–1.26)	0.012	1.06 (0.98–1.14)	0.152
Diabetes	1.61 (1.23–2.11)	0.001	1.51 (1.21–1.89)	<0.001	Diabetes	1.27 (0.80–2.00)	0.307	1.21 (0.84–1.74)	0.303
Smoking	1.30 (0.98–1.72)	0.065	1.35 (1.07–1.69)	0.01	Smoking	1.34 (0.86–2.09)	0.201	1.39 (0.98–1.98)	0.064
LVEF, per 5%	0.93 (0.89–0.97)	0.002	0.90 (0.87–0.94)	<0.001	LVEF, per 5%	0.93 (0.87–1.00)	0.062	0.94 (0.89–0.99)	0.03

HRs are adjusted. N ¼ 2,349; no ischemia on stress CMR, n ¼ 1,944. Statistical analysis by Cox proportional hazards regression.

Abbreviations: as in Tables 1 and 2.