An interaction effect observed between valence (i.e., trials with positive versus negative predictions) and anxiety group (low versus moderate) for activity in the anterior insula related to prediction certainty
The images consist of a color-rendered statistical map superimposed on a standard (MNI 1 × 1 × 1 mm) brain. Voxel-wise statistics were performed using non-parametric permutation testing within a mask of the anterior insula and periaqueductal gray, with significant results determined by p < 0.05 (corrected for multiple comparisons within the mask). Bar plots represent mean ± SE for the individual contrast estimates within the significant voxels, plotted separately for each side of the anterior insula. See also Figures S4–S7.