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. 2021 Dec 14;2021:2895893. doi: 10.1155/2021/2895893

Figure 4.

Figure 4

Targeting relationship between miR-138 and PDK1. (a) Verification of the binding site between miR-138 and using PDK1 dual-luciferase reporter gene experiment; ∗∗P < 0.01vs. the NC group. (b) Assessment of the expression of PDK1 in PBMC of patients with OS and normal people using qRT-PCR; ∗∗∗P < 0.001. (c) Determination of the expression of PDK1 in PBMC of patients with OS and normal persons using Western blot; ∗∗P < 0.01. (d) Evaluation of the expression of PDK1 in CD4+CXCR5+ Tfh cells of patients with OS using qRT-PCR; ∗∗P < 0.01vs. NC mimics; ##P < 0.01vs. NC inhibitor. (e) Correlation analysis of the relationship between miR-138 and PDK1 expression.