Figure 7.

PLF-1 blocking accelerated skeletal muscle dysfunction and remodeling on day 14 after CTX injection. (a) Grip strength was calculated in both groups. (b) The changes of workload in the vertical direction were evaluated in both groups as described in Materials and Methods. (c-e) Quantitative data showing the cross-sectional area of muscle fiber size and interstitial fibrosis (9 × 10⁴ μm²). Results are mean ± SE (n = 6–7). ^∗p < 0.05 and ^∗∗p < 0.01 by two-way repeated-measures ANOVA and Tukey's post hoc tests or Student's t-test.