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. 2021 Dec 22;38(3):110242. doi: 10.1016/j.celrep.2021.110242

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© 2021 The Author(s)

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Single-cell antibody repertoire features and clonal expansion analysis

(A) SHM rates per isotype across all datasets. Error bars represent means ± SEs.

(B) Isotype usage in single-cell repertoires sequencing data of our patient cohort (error bars represent means ± SEs).

(C) Clonal expansion profiles across all patients showing the 10 most expanded clones, colored by isotype. Error bars represent means ± SEs.

(D and E) V (D) and (E) J gene usage of HC compared to previously reported repertoire sequencing datasets from patients with COVID-19 and a healthy control. Error bars represent means ± SEs.