Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Mammalian display enables antibody screening of selected clonal lineages
(A) HDR templates are synthesized and transfected into PnP-hybridoma cell lines through CRISPR-Cas9 into the endogenous VH locus.
(B and C) After sorting by flow cytometry for successful integration with Strep-Tactin and anti-human IgG (B), (C) enriched hybridoma pools (pools A and B) are sorted for binding to SARS-CoV-2 S1 or S2.
