Figure 4.
Protein interaction network for the most significantly bound coronal proteins differentially associated with AuNP1 & AuNP3 (proteins with a fold change cut-off below 0.5 and above 1.5, and with a P-value < 0.05). The most significantly associated proteins identified in the corona formation were mainly involved in blood coagulation intrinsic pathways, opsonization, complement and coagulation cascades, and cholesterol metabolism pathways.