Table 2.
Top 20 significantly up-regulated and down-regulated lncRNAs
| Probe Set ID | p | FC (abs) | Regulation | PSTT1 | PSTT2 | PSTT3 | PSTT4 | Villi1 | Villi2 | Villi3 | Villi4 | GeneSymbol | NonCodeID |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TC0600002926.oe.1 | 2.876E-05 | 801.27435 | up | 14.57266 | 17.61935 | 14.21191 | 15.35068 | 5.161994 | 5.335738 | 5.820837 | 6.851423 | lnc-LAMA4-4 | NONHSAT114519 |
| TC0500001030.oe.1 | 2.075E-05 | 734.45276 | up | 14.62951 | 16.50723 | 16.46539 | 13.9997 | 5.054627 | 5.078194 | 6.540246 | 6.846658 | lnc-COMMD10-8 | NONHSAT103347 |
| TC0300003446.oe.1 | 0.0001658 | 650.9045 | up | 18.86095 | 18.16658 | 18.05667 | 18.81532 | 7.498871 | 7.042424 | 10.36552 | 11.6075 | lnc-TNK2-9 | NONHSAT094251 |
| TC0300003445.oe.1 | 8.53E-05 | 460.6303 | up | 16.55804 | 15.36818 | 15.39982 | 16.55225 | 5.795643 | 5.417085 | 8.381965 | 8.893738 | lnc-TNK2-10 | NONHSAT094250 |
| TC0500001029.oe.1 | 6.498E-05 | 330.9917 | up | 12.91026 | 15.37042 | 15.56427 | 12.90601 | 6.14006 | 4.675454 | 6.697259 | 5.755586 | lnc-COMMD10-9 | NONHSAT103345 |
| TC0400000688.oe.1 | 5.345E-05 | 202.31433 | up | 14.13912 | 16.11971 | 14.57873 | 14.29385 | 6.061105 | 6.281838 | 7.472301 | 8.674349 | lnc-COPS4-1 | NONHSAT097204 |
| TC0500002484.oe.1 | 0.0034374 | 105.16381 | up | 10.39773 | 11.63986 | 14.5663 | 7.646206 | 4.406109 | 4.058787 | 4.508239 | 4.410984 | RP11-78C3.1 | NONHSAT102500 |
| TC0900000988.oe.1 | 0.0005695 | 100.53162 | up | 14.10921 | 16.4567 | 17.14165 | 16.3712 | 8.728636 | 7.745153 | 11.29517 | 9.703777 | lnc-TRIM32-11 | NONHSAT134431 |
| TC0900002221.oe.1 | 0.0005368 | 99.72805 | up | 12.96074 | 14.52683 | 14.38401 | 14.13185 | 6.12572 | 5.533823 | 9.488853 | 8.295328 | PAPPA-AS1 | NR_103711 |
| TC0400002102.oe.1 | 0.0004868 | 89.59299 | up | 11.60127 | 15.63266 | 14.06496 | 13.14861 | 6.616827 | 6.794709 | 6.660107 | 8.434599 | lnc-LIN54-3 | NONHSAT097205 |
| TC0500002714.oe.1 | 0.001948 | 86.06065 | up | 10.93789 | 13.99877 | 12.5951 | 8.366644 | 4.825502 | 4.857947 | 5.668418 | 4.837413 | lnc-ATG12-2 | NONHSAT103341 |
| TC1300001424.oe.1 | 0.0055827 | 71.04717 | up | 11.47673 | 10.99826 | 10.81088 | 16.38293 | 5.018981 | 5.45683 | 7.269685 | 7.320484 | RP11-318G21.4 | NONHSAT034434 |
| TC0300003444.oe.1 | 9.85E-05 | 56.742313 | up | 12.1657 | 10.80384 | 11.8323 | 12.61162 | 5.355786 | 5.137434 | 6.225355 | 7.389472 | lnc-TNK2-11 | --- |
| TC1400000340.oe.1 | 0.002576 | 54.023994 | up | 7.73035 | 11.65167 | 12.14659 | 8.160899 | 3.831198 | 4.072921 | 4.663983 | 4.099294 | lnc-LRR1-6 | NONHSAT036699 |
| TC0400000156.oe.1 | 0.000826 | 53.37624 | up | 9.918715 | 12.84252 | 12.94642 | 13.54016 | 5.980694 | 5.678541 | 7.029627 | 7.606449 | lnc-CPZ-1 | --- |
| TC1500001204.oe.1 | 0.000714 | 52.510838 | up | 12.26639 | 8.419676 | 12.00192 | 11.29106 | 4.842388 | 5.158345 | 5.542342 | 5.577796 | RP11-73C9.1 | NONHSAT040839 |
| TC0100001151.oe.1 | 0.0125757 | 51.62064 | up | 12.92449 | 13.55079 | 13.03012 | 11.93119 | 6.584359 | 11.71653 | 4.420371 | 5.955827 | lnc-IFI44-5 | NONHSAT004079 |
| TSUnmapped00002029.oe.1 | 0.0041549 | 51.021782 | up | 14.78756 | 9.150758 | 13.04631 | 11.74117 | 6.185886 | 7.775435 | 6.255181 | 5.817128 | lnc-RTDR1-1 | --- |
| TC1200003068.oe.1 | 0.0001133 | 48.14622 | up | 9.09206 | 12.02009 | 10.97622 | 11.14791 | 5.561361 | 4.952483 | 5.211253 | 5.153783 | lnc-HCAR3-1 | NONHSAT031531 |
| TC1600001762.oe.1 | 0.006927 | 43.289265 | up | 14.51361 | 12.54379 | 14.508 | 11.07535 | 8.799093 | 10.1918 | 6.002627 | 5.903477 | lnc-KIAA0430-2 | NONHSAT140763 |
| TC0500002493.oe.1 | 0.0370893 | 288.59473 | down | 5.638968 | 5.017736 | 4.947758 | 5.209421 | 7.599888 | 8.595558 | 18.266 | 19.04404 | lnc-EDIL3-6 | NONHSAT102523 |
| TC1100001750.oe.1 | 0.0011976 | 95.452 | down | 5.716751 | 6.666399 | 6.126871 | 5.764963 | 10.45444 | 10.97112 | 14.49622 | 14.66002 | NONHSAG007410 | NONHSAT017479 |
| TC0200004232.oe.1 | 4.448E-05 | 75.3497 | down | 8.218021 | 9.405064 | 9.379367 | 9.757372 | 16.38943 | 16.15815 | 14.58752 | 14.56685 | lnc-GCG-3 | NONHSAT075191 |
| TC0500002278.oe.1 | 5.254E-05 | 73.73616 | down | 7.36856 | 5.65632 | 6.768617 | 6.701671 | 11.46042 | 12.73857 | 13.50097 | 13.61241 | lnc-CENPK-2 | NONHSAT101743 |
| TC0200004231.oe.1 | 6.523E-05 | 66.59564 | down | 8.589523 | 9.65343 | 9.179054 | 9.526411 | 16.27332 | 16.25944 | 14.06544 | 14.57964 | lnc-GCG-4 | NONHSAT075190 |
| TC0Y00000312.oe.1 | 3.009E-05 | 48.222668 | down | 7.416726 | 7.051343 | 7.681014 | 7.152988 | 13.70421 | 13.75827 | 11.88662 | 12.31953 | lnc-HSFY2-10 | NONHSAT139611 |
| TC0500000786.oe.1 | 0.0003598 | 45.157536 | down | 8.937391 | 8.656306 | 9.234922 | 11.02877 | 16.14978 | 15.59811 | 13.88346 | 14.21362 | lnc-XRCC4-6 | NONHSAT102522 |
| TC1200000179.oe.1 | 0.013569 | 35.71296 | down | 8.367052 | 8.457984 | 10.00808 | 9.479094 | 17.09085 | 16.33409 | 11.90496 | 11.61581 | lnc-RIMKLB-1 | NONHSAT026363 |
| TC0900001993.oe.1 | 0.0428375 | 34.091114 | down | 15.47735 | 10.6726 | 13.60676 | 6.988581 | 16.36274 | 14.92022 | 18.08391 | 17.74372 | lnc-OMD-1 | NONHSAT133188 |
| TC14000659.hg.4 | 0.0052727 | 30.134325 | down | 6.758659 | 6.755126 | 8.207018 | 6.675376 | 10.21877 | 10.03378 | 13.81844 | 13.97853 | MEG8 | NR_024149 |
| TC1200000178.oe.1 | 0.0203783 | 25.076464 | down | 6.339385 | 7.046954 | 8.730094 | 8.730531 | 14.91692 | 14.49464 | 10.01952 | 10.00893 | lnc-RIMKLB-3 | NONHSAT026360 |
| TC1400000032.oe.1 | 4.427E-05 | 23.937801 | down | 5.908465 | 6.809318 | 6.180269 | 6.861191 | 10.77885 | 10.08512 | 11.60237 | 11.61778 | lnc-APEX1-3 | NONHSAT035586 |
| TC0800000155.oe.1 | 0.0219285 | 21.791851 | down | 7.052204 | 6.485874 | 7.214129 | 7.360553 | 13.46182 | 14.35795 | 8.499699 | 9.576158 | lnc-PDGFRL-3 | NONHSAT125277 |
| TSUnmapped00000268.oe.1 | 0.0018863 | 21.46142 | down | 6.592407 | 6.48301 | 7.71503 | 7.08154 | 10.66954 | 9.543282 | 12.30839 | 13.04547 | lnc-DLK1-5 | --- |
| TC1400000966.oe.1 | 0.0049216 | 20.716341 | down | 6.727886 | 6.515725 | 6.867692 | 6.953129 | 9.094263 | 9.745587 | 12.64482 | 13.07055 | OTTHUMG00000029060 | NONHSAT039835 |
| TC0500001872.oe.1 | 0.0040102 | 19.861301 | down | 9.433871 | 6.534947 | 7.719427 | 6.949482 | 13.23098 | 13.10029 | 10.4047 | 11.14931 | lnc-TAS2R1-24 | NONHSAT100322 |
| TC0300002485.oe.1 | 0.0014715 | 19.597805 | down | 7.21331 | 7.91722 | 7.539716 | 7.546046 | 13.63197 | 12.58882 | 10.73676 | 10.42922 | lnc-PRICKLE2-6 | NONHSAT090260 |
| TC0800000049.oe.1 | 1.843E-05 | 18.799055 | down | 7.130774 | 5.713998 | 6.799021 | 6.786564 | 11.20656 | 10.67594 | 10.49293 | 10.98528 | lnc-MCPH1-3 | NONHSAT124787 |
| TC0600001704.oe.1 | 0.0002245 | 17.906603 | down | 6.236846 | 4.643425 | 6.369543 | 5.58888 | 9.445736 | 9.72422 | 10.91174 | 9.406675 | lnc-SLC22A1-6 | NONHSAT115901 |
| TSUnmapped00000213.oe.1 | 0.006309 | 17.698973 | down | 6.089841 | 7.533654 | 7.496603 | 6.496414 | 13.19711 | 12.04852 | 9.260924 | 9.692332 | lnc-COLEC10-1 | --- |
P values were calculated using unpaired t-test and adjusted for multiple comparison. FC (abs): the absolute ratio (no log scale) of average normalized intensities between PSST and normal villi. PSTT 1 to 4 and Villi 1 to 4: each sample's normalized intensity (log2 scale). The same goes for the follow-up table.