Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jan 1;18(1):30–42. doi: 10.7150/ijbs.65255

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The author(s)

This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.

PMC Copyright notice

IRF7 suppresses OS cell proliferation and promotes cell apoptosis. (A) The growth rate of over-vector and over-IRF7 Saos-2 and MNNG-HOS was monitored by the plate colony formation assay. (B) The growth rate of sh-Ctrl and sh-IRF7 KHOS cells in the complete medium was determined by the plate colony formation assay. (C) In the culture medium, glucose was replaced by galactose; then, the growth rate of sh-Ctrl and sh-IRF7 KHOS cells in culture was determined by the plate colony formation assay. (D) The cell cycle status of over-vector and over-IRF7 Saos-2 and MNNG-HOS cells was analyzed by flow cytometry. (E) The cell cycle status of sh-Ctrl and sh-IRF7 KHOS cells was analyzed by flow cytometry. (F) The cell apoptosis status of over-vector and over-IRF7 Saos-2 and MNNG-HOS upon serum starvation for 24 h was determined by the Caspase3-7 activity assay. (G) The cell apoptosis status of sh-Ctrl and sh-IRF7 KHOS upon serum starvation for 24 h was determined by the Caspase3-7 activity assay. *P < 0.05; **P < 0.01; ***P < 0.001.