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. 2022 Jan 1;18(1):112–123. doi: 10.7150/ijbs.63388

Figure 1.

Figure 1

Rab31 is highly expressed in cervical cancer cells and tissues. (A) qRT-PCR was used to detect the mRNA level of Rab31 in different cells, and the mRNA level of Rab31 was higher in cervical cancer cells than in non-cancer HaCaT cells. (B) Rab31 protein level was detected by Western blotting, and Rab31 was highly expressed in cervical cancer cells. (C) Western blotting of Rab31, p53 and pRb in HPV16 E6- and E7-expressing RPE1 cells was shown. (D-F) Detection of Rab31, p53 and pRb protein levels in HeLa, SiHa and CaSki cells after transfection with siRNA targeting HPV18 E6, 18 E6E7 or 16 E6, 16 E6E7. (G) Detection of Rab31 mRNA level in 55 non-cancer cervical tissues and 66 cervical cancer tissue specimens using qRT-PCR, and Rab31 was highly expressed in cervical cancer tissues. *P <0.05, **P <0.01.