Table 3.
Correlation between alpha-SMA expression and clinical features of iCCA patients
| Index | iCCA | ||
|---|---|---|---|
| Low alpha-SMA expression | High alpha-SMA expression | P | |
| Sex | |||
| Female | 9 | 4 | 0.1809 |
| Male | 12 | 17 | |
| Age | |||
| < 60 | 13 | 10 | 0.5359 |
| ≥ 60 | 8 | 11 | |
| Tumor number | |||
| 1 | 19 | 17 | 0.6628 |
| >1 | 2 | 4 | |
| Tumor size | |||
| < 5 | 15 | 8 | 0.0616 |
| ≥ 5 | 6 | 13 | |
| AFP | |||
| < 25 | 18 | 19 | 0.999 |
| ≥ 25 | 3 | 2 | |
| CA19-9 level | |||
| < 37 | 6 | 6 | 0.999 |
| ≥ 37 | 15 | 15 | |
| Cirrhosis | |||
| (-) | 17 | 17 | 0.999 |
| (+) | 4 | 4 | |
| Histology | |||
| I-II, II | 10 | 7 | 0.5303 |
| II-III, III | 11 | 14 | |
| Vascular invasion | |||
| (-) | 16 | 8 | 0.0278* |
| (+) | 5 | 13 | |
| miR-206 expression | |||
| Low | 2 | 19 | <0.001* |
| High | 19 | 2 | |
*as P<0.05.