TABLE 3.

Treatment success based on varying cut‐offs for the decrease in the total client specific outcome measures scores at day 56

	Decrease in total CSOM score vs day 0 (cut‐off for treatment success)
% of cats with treatment success	≥2	≥3	≥4	≥5 a
Placebo group	64.65	52.77	39.40	29.74
Frunevetmab group	75.91	69.29	58.32	43.61
P‐value	0.031*	0.018*	0.012*	0.032*
Treatment effect b	11.26%	16.52%	18.92%	13.87%
NNT	8.9	6.1	5.3	7.2

Note: Statistical comparison (P‐value) and treatment effect is also shown for each cut‐off.

Abbreviation: NNT, number needed to treat.

^a Frunevetmab n = 8 and placebo n = 2 could not be included in the analysis because CSOM scores were <8 at baseline, meaning they could not improve by ≥5 (lowest score possible on CSOM was 3).

^b Calculated using the formula [treatment effect minus placebo effect]/[placebo effect] expressed as a percentage.

^*Significant P‐value.