TABLE 7.

Change in total pain scores from screening (least squares [LS] means and SEM) from orthopedic evaluation by veterinarians, and statistical comparisons at each time point

Study day	Group	N	LS means (SEM)	P‐value
28	Placebo	92	−4.7 (0.6)	.3
	Frunevetmab	178	−5.3 (0.6)
56	Placebo	89	−5.0 (0.7)	.02
	Frunevetmab	175	−6.4 (0.6)
84	Placebo	83	−5.3 (0.7)	.04
	Frunevetmab	166	−6.6 (0.6)
Overall	Placebo	264	−5.0 (0.6)	.04
	Frunevetmab	519	−6.1 (0.5)

Abbreviation: N, number of animals.