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. 2021 Nov 5;35(6):2812–2820. doi: 10.1111/jvim.16308

FIGURE 1.

FIGURE 1

Box and whiskers plots for urinary (u) biomarkers (γ‐glutamyl transpeptidase [GGT], alkaline phosphatase [ALP], heat‐shock protein 70 [HSP70], and interleukin [IL] ‐6 and ‐18) as predictors of acute kidney injury (AKI) development during hospitalization. Five urinary biomarkers were measured at presentation in nonazotemic hospitalized dogs (n = 118; 15 dogs developed AKI during hospitalization and 103 without AKI). Healthy dogs constituted the control group (n = 20). The box extends from the 25th to the 75th percentiles, while the whiskers extend 1.5 times the interquartile range on either side of the box. The study population significantly differed from the controls for all biomarkers (P < .001). For AKI development, uGGT/uCr, uHSP70/uCr, and uIL‐6/uCr significantly differed between groups (P = .02, P = .04 and P = .001, respectively)