TABLE 2.

Receiver operator characteristic analyses for uIL‐6/uCr, uGGT/uCr, and uHSP70/uCr at presentation to the hospital as predictors of development of acute kidney injury during hospitalization

	uIL‐6/uCr (pg/mg)	uGGT/uCr (U/g)	uHSP/uCr (ng/mg)
AUROC (95% CI)	0.78 (0.65‐0.91)	0.68 (0.55‐0.81)	0.67 (0.51‐0.83)
Optimal cutoff value a (sensitivity/specificity)	118 (79%/73%)	121 (79%/54%)	3.8 (79%/54%)
Additional cutoffs (sensitivity/specificity)	30 (93%/32%)	90 (93%/41%)	1.4 (93%/26%)
	204 (64%/82%)	171 (57%/73%)	10.1 (50%/79%)
	1478 (29%/96%)	281 (21%/85%)	32.3 (29%/92%)

Abbreviations: AUROC, area under the receiver operator characteristic curve; CI, confidence interval; GGT, gamma‐glutamyl transpeptidase; HSP, heat shock protein; IL, interleukin; u, urinary.

^a The maximal point of the Youden index (Sen‐[1‐Spec]) was used as the optimal cutoff value.