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. 2021 Dec 22;2021(12):CD006614. doi: 10.1002/14651858.CD006614.pub4

Ahmed 2015.

Methods Parallel randomised control trial
Participants Location: 1 hospital in Egypt
Timeframe: July 2012 to December 2013
Eligibility: 452 women with a singleton pregnancy (228 intervention, 224 control) undergoing an elective caesarean section from 37 + 0 weeks' gestation to 39 + 6 weeks' gestation.
Exclusion: women with multiple gestations or a fetus with a major congenital anomaly and those with other medical or obstetrical conditions warranting early or immediate delivery and/or women who had received prophylactic dexamethasone during the current pregnancy were excluded.
Interventions Intervention: 2 doses of 12 mg IM dexamethasone administered 24 hours apart (n = 228)
Control group: usual care (without antenatal steroids) (n = 224)
Outcomes
  • Rates of RDS

  • Rates of TTN

  • Severity of RDS* (mild, moderate or severe according to the level of oxygen or ventilatory support)

  • Rates of admission to the NICU

Notes All participants in the intervention group received the antenatal corticosteroids at 37 weeks' gestation irrespective of gestational age at delivery.
* severity of RDS was only assessed for the NICU admitted cases.
Funding source of study and declarations of interest: "The authors report no conflict of interest or financial support."
We contacted the trial authors in January 2021 to ask for more information about their trial registration and randomisation processes. Awaiting reply.
Not included in 2021 update because of lack of response from trial authors regarding our trustworthiness criteria (trial published since 2010 without prospective registration)