Table 1.
Demographic, baseline, procedural, and outcome characteristics
| n (%) | |
|---|---|
| Demographic characteristics (n = 139) | |
| Age, mean (SD) (years) | 76.0 (10.9) |
| Female sex | 82 (59.0) |
| Premedication | |
| Antiplatelet therapy | 50 (36.0) |
| Oral anticoagulant therapy | 22 (15.8) |
| Statin | 39 (28.1) |
| Vascular risk factors | |
| Hypertension | 115 (82.7) |
| Diabetes mellitus | 34 (24.5) |
| Hyperlipidemia | 37 (26.6) |
| Smoking | 22 (15.8) |
| Atrial fibrillation | 46 (33.1) |
| Peripheral artery occlusive disease | 14 (10.1) |
| Premorbid mRS score | |
| 0 | 47 (33.8) |
| 1 | 34 (24.5) |
| 2 | 20 (14.4) |
| > 2 | 38 (27.3) |
| NIHSS score | |
| Mean (SD) | 14.3 (7.5) |
| Median (IQR) | 14.0 (8–20) |
| Site of arterial occlusion | |
| ICA occlusion | 43 (27.2) |
| MCA occlusion | 95 (68.3) |
| ICA + MCA occlusion | 38 (23.6) |
| Left side | 70 (43.5) |
| Treatment | |
| Alteplase only | 6 (4.3) |
| Alteplase + EST | 81 (58.3) |
| EST only | 52 (37.4) |
| Door-to-needle time, mean (SD)a (min) | 32.0 (13.0) |
| Pretreatment ASPECTSb | |
| 8–10 | 89 (65.9) |
| 6–7 | 31 (23.0) |
| < 6 | 15 (11.1) |
| Median (IQR) | 8 (7–10) |
| Periinterventional aspects | |
| Conversion to general anesthesiac | 14 (10.1) |
| Need of sedation | 127 (91.4) |
| Need of catecholamines | 43 (30.9) |
| MAP reduction of at least 20%d | 67 (49.3) |
| MAP reduction of at least 30%d | 33 (24.3) |
| MAP reduction of at least 40%d | 13 (9.6) |
| MAP < 70 mm Hg | 7 (5.0) |
| Functional outcome parameters (n = 139) | |
| NIHSS score change after 24 h, mean (SD) | − 3.8 (9.0) |
| mRS score after 3 mo | |
| 0–1 | 37 (26.6) |
| 0–2 | 77 (55.4) |
| 0–3 | 80 (57.6) |
| In-house mortality | 10 (7.2) |
| Mortality after 3 mo | 28 (20.1) |
| Degree of reperfusion (TICI grade) (n = 161e) | |
| 0–2a | 22 (13.6) |
| 2b | 70 (43.5) |
| 2c | 19 (11.8) |
| 3 | 50 (31.1) |
ASPECTS, Alberta stroke program early computed tomographic score, EST, endovascular stroke treatment, ICA, internal carotid artery, IQR, interquartile range, MAP, mean arterial pressure, MCA, middle cerebral artery, mRS, modified Rankin Scale, NIHSS, National Institutes of Health Stroke Scale, SD, standard deviation, TICI, thrombolysis in cerebral infarction
aData are missing in 41 patients
bASPECTS were missing in 4 patients
cReasons for conversion are shown in Supplementary Table 2
dData are missing in 3 patients
eData from the whole study population are shown here