Table 1.
Patient Demographics and Clinical Laboratory Assessment
| Physiologic Lysis (n=10) | Hyperfibrinolysis (n=10) | Shutdown (n=10) | |
|---|---|---|---|
| Median (Q1–Q3) | Median (Q1–Q3) | Median (Q1–Q3) | |
| Age (years) | 36.4 (23.4–59.6) | 32.3 (24.6–43.4) | 36.4 (30.3–44.9) |
| Men (%) | 90% | 80% | 80% |
| Blunt Mechanism (%) | 30% | 60% | 50% |
| NISS | 17.0 (9.0–22.0) | 46.5 (38.0–51.8) | 17.0 (14.5–27.0) |
| Max AIS | |||
| Head/Neck | 0.0 (0.0–0.0) | 0.0 (0.0–3.5) | 0.0 (0.0–1.8) |
| Chest | 0.0 (0.0–3.0) | 3.5 (3.0–5.0) | 0.0 (0.0–2.3) |
| Abdomen/Pelvis | 0.0 (0.0–3.0) | 2.0 (0.0–3.5) | 1.0 (0.0–3.0) |
| Extremities | 0.0 (0.0–2.0) | 1.0 (0.0–2.3) | 0.0 (0.0–2.0) |
| 1st Measurement (ED) | |||
| SBP (mm Hg) | 128.0 (99.5–132.0) | 86.0 (82.0–130.0) | 110. (100.0–138.0) |
| GCS | 15.0 (9.0–15.0) | 3.0 (3.0–3.0) | 15.0 (12.5–15.0) |
| pH | 7.3 (7.3–7.3) | 6.9 (6.8–7.2) | 7.3 (7.3–7.3) |
| Base Excess (mEg/L) | −5.0 (−7.0, −2.0) | −11.0 (−17.0, −3.0) | −8.0 (−8.8, −5.8) |
| Hematocrit (%) | 40.3 (38.9–44.0) | 31.4 (27.6–37.4) | 40.4 (38.2–41.1) |
| INR | 1.1 (1.1–1.2) | 2.0 (1.8–3.4) | 1.1 (1.1–1.2) |
| PTT | 27.5 (25.3–28.2) | 66.1 (20.6–98.9) | 25.8 (23.9–28.0) |
| Fibrinogen | No Data | 68.0 (49.6–107.0) | 143.0 (122.0–164.0) |
| % Death | 0% | 70% | 0% |
| CNTEG+tPA | |||
| R | 7.8 (6.9–8.4) | 8.3 (6.6–12.9) | 6.4 (4.5–7.7) |
| Angle | 60.7 (58.2–61.9) | 48.2 (28.0–50.1) | 65.9 (62.2–71.1) |
| MA | 60.0 (57.8–62.5) | 20.3 (14.0–31.6) | 62.0 (55.6–64.3) |
| LY30 | 7.6 (6.9–8.3) | 80.0 (73.0–88.9) | 1.1 (0.5–1.5) |