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. 2021 Dec 21;11:24379. doi: 10.1038/s41598-021-03865-w

Table 3.

The effect of the lowest in-hospital albumin level on the clinical outcome of 1055 patients.

Variable Hypoproteinemia group (n = 924) Normal group (n = 131) P univariate P multivariate
The time without vasoactive drugs 3.6 (1.6–9.3) 2.3 (1.3–5.1)  < 0.01  < 0.01
The time without mechanical ventilation 2.3 (1.2–4.2) 2.0 (1.2–3.5) 0.17  < 0.01
ICU stay 6.0 (2.7–13.0) 3.5 (1.8–7.0)  < 0.01 0.55
Hospital stay 13.7 (7.1–24.1) 8.1 (5.3–12.3)  < 0.01 0.63

In multivariate regression analysis, the influences of factors (such as SAPSII score, septic shock, chronic kidney disease, diabetes, hemoglobin, platelets, serum albumin, the lowest in-hospital albumin level, albumin supplementation, use of vasoactive drugs, and mechanical ventilation) were excluded.