Table 4.
Baseline situation of the two groups with and without albumin supplementation after propensity matching analysis.
| Variable | Albumin supplementation (A) (n = 280) |
No albumin supplementation (B) (n = 280) |
P |
|---|---|---|---|
| Age, median (IQR) | 65.9 (55.9–78.2) | 67.1 (53.8–79.9) | 0.97 |
| Male, n (%) | 167 (59.6) | 156 (55.7) | 0.35 |
| BMI, median (IQR) | 28.4 (25–32.7) | 27.7 (22.7–31.9) | 0.04 |
| SOFA score, median (IQR) | 8 (5–11) | 8 (6–11) | 0.58 |
| SAPSII score, median (IQR) | 49 (39–58) | 50 (37–61) | 0.37 |
| Sepsis, n (%) | |||
| Septic shock | 192 (68.5) | 206 (73.5) | 0.19 |
| Severe sepsis | 280 | 280 | |
| Comorbidities, n (%) | |||
| COPD | 4 (1.4) | 8 (2.8) | 0.24 |
| Coronary heart disease | 44 (15.7) | 41 (14.6) | 0.72 |
| Hypertension | 120 (42.8) | 107 (38.2) | 0.26 |
| Heart failure | 71 | 71 | |
| Cerebrovascular accident | 1 | 1 | |
| Chronic kidney disease | 48 (17.1) | 57 (20.3) | 0.33 |
| Diabetes | 86 (30.7) | 74 (26.4) | 0.26 |
| Laboratory examination on admission, median (IQR) | |||
| White blood cells (109/L) | 12.3 (7.4–17.6) | 12.9 (7.4–19.8) | 0.64 |
| Hemoglobin (g/dL) | 10.2 (9–11.9) | 10.4 (9.1–12) | 0.70 |
| Platelets (109/L) | 178 (112–268) | 167 (100–263) | 0.30 |
| Blood potassium (mmol/L) | 4.1 (3.6–4.6) | 4 (3.6–4.6) | 0.67 |
| Blood sodium (mmol/L) | 138 (134–142) | 137 (133–141) | 0.18 |
| Blood sugar, (mg/dL) | 127 (99–165) | 129 (104–170) | 0.49 |
| Serum albumin (g/dL) | 2.4 (2–2.8) | 2.5 (2.1–2.8) | 0.84 |
| Blood lactic acid (mmol/L) | 2.1 (1.4–3.4) | 2.2 (1.3–3.4) | 0.70 |
| Blood creatinine (mg/dL) | 1.4 (0.9–2.5) | 1.4(0.9–2.4) | 0.85 |
| The lowest in-hospital albumin level (g/dL), median (IQR) | 2.1 (1.8–2.5) | 2.1 (1.9–2.5) | 0.71 |
| The use of vasoactive drugs, n (%) | 240 (85.7) | 215 (76.7) | < 0.01 |
| The use of mechanical ventilation), n (%) | 196 (70) | 168 (60) | 0.01 |