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. 2021 Dec 21;11:24379. doi: 10.1038/s41598-021-03865-w

Table 5.

The effect of albumin supplementation for hypoalbuminemia on the results of the study.

Variable Albumin supplementation (A)
(n = 280)
No albumin supplementation (B)
(n = 280)
P univariate P multivariate
Mechanical ventilation time % 43.1 (7.9–77.8) 32.9 (0–66.6) 0.01 0.57
Vasoactive drugs time, % 18.4 (4.1–40.4) 13.3 (0.7–34.4) 0.03 0.89
AKI, n (%) 217 (80.3) 195 (69.6) 0.04 0.06
ICU stay, day, median (IQR) 10.6 (4.4–18.6) 5.2 (2.6–11.6)  < 0.01  < 0.01
Hospital stay, day, median (IQR) 21.5 (12.8–33.5) 10.9 (5.9–20.3)  < 0.01  < 0.01
28-day mortality rate, n (%) 111 (39.6) 105 (37.5) 0.60 0.80

In multivariate regression analysis, possible influencing factors (including BMI, septic shock, blood sodium on admission, vasoactive drugs, and mechanical ventilation) were excluded.