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Overview of Surgical Stress Response. The figure represents the neuroendorine and the inflammatory response associated with surgery. After surgical incision, there is an increase of cortisol and cathecholamines. Additionally, there is a profound inflammatory response folllowed by immunosupression. All these together enables cancer cells to growth, proliferate and produce distant metastasis. NK, natural killer cell, TAN, tumor associated neutrophiles, Tregs, regulartoy T cells.
