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. 2021 Jul 20;16(1):178–189. doi: 10.1038/s41396-021-01053-2

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — A Temporal abundance trends. The X axis presents the month and the Y axis presents the centered logarithm ratio abundance. A generalized additive model smooth is adjusted to the data points. B Heatmaps presenting the nucleotide divergence between each ASV pair (number of mismatches after alignment). Five nucleotide divergence equals to a median sequence identity of 98.8%.