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. 2021 Dec 8;15:747951. doi: 10.3389/fnins.2021.747951

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Copyright © 2021 Nakagawa-Tamagawa, Kirino, Sugao, Nagata and Tagawa.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Blockade of CaM-binding but not CaN-binding rescues the migration deficit. (A,B) GFP images and histograms of the Cav1.2^{I1166T/I1624A} (A) and Cav1.2^{I1166T/A1929P} group (B), as shown in Figure 2A. (C) Histogram of the mean ± SEM are merged for Cav1.2^WT, Cav1.2^{I1166T/I1624A}, Cav1.2^{I1166T/A1929P}, and Cav1.2^I1166T/L745P groups. (D) Proportion of correctly migrated neurons (left) and that of migration-failed neurons located in WM and Middle (right). Independent values and mean ± SEM are shown. **P < 0.01; *P < 0.05; n.s., P ≥ 0.05.