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. 2021 Dec 21;11:24340. doi: 10.1038/s41598-021-03259-y

Table 1.

Patient baseline characteristics of high tibial osteotomy by age.

HTO
 < 60 60–65  > 65 P-value SMD
(N = 41,112) (N = 13,895) (N = 6138)
Age (mean (sd)) 52.62 (5.38) 62.10 (1.66) 70.13 (4.24)  < 0.001 2.829
Sex (%)  < 0.001 0.052
Female 10,948 (26.6) 3230 (23.2) 1431 (23.3)
Male 30,164 (73.4) 10,665 (76.8) 4707 (76.7)
Hypertension (%) 15,858 (38.6) 7465 (53.7) 3981 (64.9)  < 0.001 0.360
Hyperlipidemia (%) 18,933 (46.1) 8518 (61.3) 3677 (59.9)  < 0.001 0.206
Peripheral vascular disease (%) 7898 (19.2) 3915 (28.2) 2010 (32.7)  < 0.001 0.208
Diabetes_without complication (%) 8120 (19.8) 4096 (29.5) 2230 (36.3)  < 0.001 0.250
Diabetes_with complication (%) 2898 (7.0) 1579 (11.4) 930 (15.2)  < 0.001 0.174
Depression (%) 6063 (14.7) 2631 (18.9) 1277 (20.8)  < 0.001 0.106
Dementia (%) 252 (0.6) 248 (1.8) 373 (6.1)  < 0.001 0.213
Type of insurance (%) 0.68 0.083
Health insurance 39,522 (96.1) 13,563 (97.6) 5852 (95.3)
Medical benefits 1590 (3.9) 332 (2.4) 286 (4.7)
City of residence (%)  < 0.001 0.085
Over 10milion 11,345 (27.6) 4099 (29.5) 1581 (25.8)
Over 1milion 11,603 (28.2) 3736 (26.9) 1550 (25.3)
Others 18,164 (44.2) 6060 (43.6) 3007 (49.0)
Type of hospital (%)  < 0.001 0.091
Teaching hospital 4734 (11.5) 1277 (9.2) 645 (10.5)
General hospital 7369 (17.9) 2336 (16.8) 1229 (20.0)
Independent hospital 27,353 (66.5) 9603 (69.1) 3956 (64.5)
Private clinic 1656 (4.0) 679 (4.9) 308 (5.0)
CCI (%)  < 0.001 0.329
0 4617 (11.2) 733 (5.3) 271 (4.4)
1 8530 (20.7) 1760 (12.7) 663 (10.8)
2 9465 (23.0) 2835 (20.4) 1069 (17.4)
 ≥ 3 18,500 (45.0) 8567 (61.7) 4135 (67.4)
Year (%)  < 0.001 0.183
2008 1143 (2.8) 236 (1.7) 128 (2.1)
2009 1302 (3.2) 236 (1.7) 164 (2.7)
2010 1591 (3.9) 290 (2.1) 172 (2.8)
2011 2403 (5.8) 577 (4.2) 308 (5.0)
2012 3192 (7.8) 807 (5.8) 396 (6.5)
2013 4125 (10.0) 1204 (8.7) 579 (9.4)
2014 4253 (10.3) 1274 (9.2) 575 (9.4)
2015 5153 (12.5) 1626 (11.7) 750 (12.2)
2016 6039 (14.7) 2225 (16.0) 1004 (16.4)
2017 5952 (14.5) 2580 (18.6) 1008 (16.4)
2018 5959 (14.5) 2840 (20.4) 1054 (17.2)

HTO high tibial osteotomy, SMD standardised mean difference, CCI Charlson comorbidity index.

*CCI: Myocardial infarction, Congestive heart failure, Peripheral vascular disease, Cerebrovascular disease, Dementia, Chronic pulmonary disease, Connective tissue disease, Peptic ulcer disease, Mild liver disease, Moderate or severe liver disease (3), Diabetes without complications, Diabetes with complications (2), Paraplegia and hemiplegia (2), Renal disease (2), Cancer (2), Metastatic carcinoma (6), AIDS/HIV (6).