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Images showing immunohistochemical staining of CXCL12, CXCR4, and FAPα in the case of each pathways in locally advanced rectal cancer (LARC) after neoadjuvant chemoradiotherapy (LARC-nCRT) (A,C,E) and LARC with no nCRT (LARC-no nCRT) (B,D,E). In the case of LARC-nCRT, the expression of CXCL12, CXCR4, and FAPα is higher than in the case of LARC-no nCRT (original magnification 400× ; scale bar= 50 µm).
