. 2022 Jan 1;13(1):51–61. doi: 10.7150/jca.55159

Table 4.

Effect of Anemia on overall survival with using other studies' cut-off: Cox proportional hazard modeling results.

First author	No of cases	Anemia Cut Off	Outcome	Other Studies		Ours
First author	No of cases	Anemia Cut Off	Outcome	HR(95%CI)	p-value	HR(95%CI)	p-value
Holgersson et al³⁸	835	<11g/dL	OS	1.33(1.10,1.61)	0.003	1.3 (1.0, 1.7)	0.059
Pathak et al⁹	752	<12 g/dL	OS	1.51(1.03,2.21)	0.030	1.4 (1.1, 1.8)	0.002
Belbaraka et al¹¹	45	male<13g/dL,	OS	2.78(1.29,5.99)	0.009	1.4 (1.1, 1.9)	0.009
Belbaraka et al¹¹	45	female<11.5g/dL.	OS	2.78(1.29,5.99)	0.009	1.4 (1.1, 1.9)	0.009
Park et al¹³	630	male<13g/dL,	OS	1.31(1.03,1.68)	0.030	1.4 (1.1, 1.7)	0.004
Park et al¹³	630	female<12g/dL.	OS	1.31(1.03,1.68)	0.030	1.4 (1.1, 1.7)	0.004

Our cohort were adjusted for: Age; Sex; Smoking history; ECOG PS; BMI; Pathology; Differentiation; ALK fusion; EGFR mutation; Sum of metastasis organs; Treat type of 1st line therapy; Sum of treatment lines.