Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Dec 8;12:789487. doi: 10.3389/fneur.2021.789487

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Nguyen, Nam, Kang, Han, Kim, Dieterich and Oh.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Evaluation of long-term spatial reference memory with the Morris water maze (MWM). The process of hidden platform training (POD 10–13) (A) and the probe trial on POD 14 (B). Compared with the control group, the Lt.-UL mice showed longer escape latency from TD 1, 2, 3 to 4. The Rt.-UL mice showed reduced values compared with the control mice on the two last TDs. Subgroup analysis revealed that the Lt.-UL mice showed markedly longer escape latency than the Rt.-UL group in the last 3 days (C). During the probe trial on POD 14, there was a decreased percentage of time spent in the target quadrant in both Lt.-UL and Rt.-UL groups compared with the control group. The Lt.-UL mice showed a lower percentage of time in the target quadrant values compared with the Rt.-UL mice (D). The values are indicated as mean ± SD. Statistical significances were calculated using the one-way ANOVA with post-hoc tests. *Significantly different between two groups; #significantly different between three groups; *, #p < 0.05; **p < 0.01; ***, ###p < 0.001.