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. 2021 Dec 8;8:753885. doi: 10.3389/fcvm.2021.753885

Table 5.

Correlation of tumour biomarker levels, CV morbidity and mortality, and ACM.

MV correction + CRP
CV HR (95% CI) P
CA 15-3 1.10 (0.87–1.40) 0.398
CEA 1.27 (1.07–1.52) 0.006
CYFRA 21-1 1.27 (1.03–1.56) 0.021
ACM HR (95% CI) P
CA 125 1.26 (1.01–1.56) 0.037
CA 15-3 1.58 (1.16–2.15) 0.003
CEA 1.60 (1.30–1.98) 0.000
CYFRA 21-1 1.24 (0.98–1.58) 0.065

MV correction is adjusted for age, gender, BMI, smoking habits, TCL, glucose levels, SBP, prevalent CVD and CRP.

CV, cardiovascular; HR, hazard ratio; MV, multivariable; CVD, cardiovascular disease; ACM, all-cause mortality; BMI, body mass index; TCL, total cholesterol; SBP, systolic blood pressure; CA, cancer antigen; CEA, carcinoembryonic antigen; CYFRA, cytokeratin fragment.