Table 7.
Correlation of tumour biomarker levels and CV mortality, HF, CAD, and CVA.
| CV mortality | HR (95% CI) | P |
|---|---|---|
| CA 15-3 | 2.88 (1.58–5.24) | 0.001 |
| CEA | 1.87 (1.33–2.64) | 0.000 |
| CYFRA 21-1 | 1.40 (0.93–2.13) | 0.106 |
| HF | HR (95% CI) | P |
| CA 125 | 1.27 (0.95–1.71) | 0.097 |
| CA 15-3 | 1.69 (1.16–2.48) | 0.006 |
| CA 19-9 | 1.22 (1.01–1.48) | 0.036 |
| CEA | 1.28 (0.95–1.73) | 0.096 |
| CAD | HR (95% CI) | P |
| CA 125 | 1.11 (0.87–1.41) | 0.389 |
| CEA | 1.21 (0.98–1.48) | 0.070 |
| CYFRA 21-1 | 1.18 (0.91–1.53) | 0.200 |
| CVA | HR (95% CI) | P |
| CYFRA 21-1 | 1.54 (1.06–2.26) | 0.023 |
CV, cardiovascular; HR, hazard ratio; MV, multivariable; CVD, cardiovascular disease; HF, heart failure; CAD, coronary artery disease; CVA, cerebrovascular accident; BMI, body mass index; TCL, total cholesterol; SBP, systolic blood pressure; AFP, alpha-fetoprotein, CA, cancer antigen; CEA, carcinoembryonic antigen; CYFRA, cytokeratin fragment.
MV is adjusted for age, gender, BMI, smoking habits, TCL, glucose levels, SBP, prevalent CVD and CRP.