Table 5.

The correlations between CD146 and gene markers of immune cells in ccRCC and normal cells by GEPIA.

Description	Gene markers	None		Purity
		Cor	p-Value	Cor	p-Value
CD8+T cell	CD8A	-0.005	0.910	-0.033	0.475
	CD8B	-0.028	0.521	-0.058	0.217
T cell (general)	CD3D	-0.001	0.973	-0.053	0.260
	CD3E	0.053	0.221	0.011	0.810
	CD2	0.024	0.584	-0.024	0.611
B cell	CD19	0.022	0.618	-0.006	0.904
	CD79A	0.026	0.542	-0.011	0.806
Monocyte	CD86	0.016	0.717	-0.034	0.466
	CD115(CSF1R)	0.165	***	0.124	**
TAM	CCL2	0.125	**	0.122	**
	CD68	-0.020	0.641	-0.052	0.267
	IL10	0.083	0.055	0.054	0.243
M1 macrophage	INOS(NOS2)	0.554	***	0.537	***
	IRF5	-0.214	***	-0.266	***
	COX2(PTGS2)	0.227	***	0.245	***
M2 macrophage	CD163	0.191	***	0.156	***
	VSIG4	0.079	0.069	0.024	0.610
	MS4A4A	0.154	***	0.120	*
Neutrophils	CD66b(CEACAM8)	0.087	*	0.095	0.041
	CD11b(ITGAM)	0.093	*	0.055	0.240
	CCR7	0.239	***	0.195	***
NK	KIR2DL1	0.316	***	0.305	***
	KIR2DL3	0.230	***	0.214	***
	KIR2DL4	0.061	0.161	0.045	0.339
	KIR3DL1	0.309	***	0.309	***
	KIR3DL2	0.275	***	0.254	***
	KIR3DL3	0.130	**	0.109	*
	KIR2DS4	0.274	***	0.265	***
Dendritic cell	HLA-DPB1	0.080	0.066	0.032	0.499
	HLA-DQB1	0.120	**	0.087	0.062
	HLA-DRA	0.048	0.264	0.001	0.984
	HLA-DPA1	0.094	*	0.048	0.302
	BDCA-1(CD1C)	0.245	***	0.214	***
	BDCA-4(NRP1)	0.683	***	0.668	***
	CD11c	-0.032	0.455	-0.053	0.259
Th1	T-bet (TBX21)	0.338	***	0.330	***
	STAT4	0.224	***	0.181	***
	STAT1	0.027	0.533	-0.013	0.779
	IFN-γ(IFNG)	-0.066	0.128	-0.109	*
	TNF-α(TNF)	0.032	0.454	-0.003	0.950
Th2	GATA3	0.043	0.326	0.053	0.259
	STAT6	0.228	***	0.226	*
	STAT5A	0.061	0.157	0.009	0.848
	IL13	0.101	*	0.125	**
Tfh	BCL6	0.303	***	0.306	***
	IL21	0.005	0.901	0.000	1.000
Th17	STAT3	0.437	***	0.437	***
	IL17A	0.024	0.577	0.003	0.942
Treg	FOXP3	0.004	0.919	-0.042	0.369
	CCR8	0.040	0.363	0.007	0.879
	STAT5B	0.452	***	0.458	***
	TGFβ(TGFB1)	0.506	***	0.504	***
T cell exhaustion	PD-1(PDCD1)	-0.076	0.078	-0.110	*
	CTLA4	-0.075	0.083	-0.124	**
	LAG3	-0.094	*	-0.133	**
	TIM3(HAVCR2)	0.024	0.578	-0.002	0.965
	GZMB	0.213	***	0.209	***

*p < 0.05. **p < 0.01. ***p < 0.001.