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. 2021 Dec 8;9:769881. doi: 10.3389/fcell.2021.769881

TABLE 2.

Difference of CT characteristics and gene status between low-risk subtype and high-risk subtype.

Characteristics Low-risk subtype n = 412 High-risk subtype n = 72 p Value
CT characteristics <0.001
GGO components 323 (78.4) 36 (50.0)
Pure solid 89 (21.6) 36 (50.0)
EGFR gene mutation <0.001 a
Negative 92 (22.3) 34 (47.2)
Positive 198 (48.1) 20 (27.8)
Unknown 122 (29.6) 18 (25.0)
ALK rearrangement 0.017 a
Negative 273 (66.3) 47 (65.3)
Positive 6 (1.5) 5 (6.9)
Unknown 133 (32.3) 72 (27.8)

EGFR, epidermal growth factor receptor; ALK, anaplastic lymphoma kinase; CT, computed tomography; GGO, ground-glass opacity.

a

The p value was calculated excluded the patients with unknown EGFR and ALK status.