TABLE 3.
Difference of LUAD subtype and gene status between GGO and pure solid nodule.
| Characteristics | GGO component n = 359 | Pure solid n = 125 | p Value |
|---|---|---|---|
| Pathologic subtype | <0.001 | ||
| Low-risk subtype | 323 (90.0) | 89 (71.2) | |
| High-risk subtype | 36 (10.0) | 36 (28.8) | |
| EGFR gene mutation | <0.001 a | ||
| Negative | 73 (20.3) | 53 (42.4) | |
| Positive | 169 (47.1) | 49 (39.2) | |
| Unknown | 117 (32.6) | 18 (18.4) | |
| ALK rearrangement | 0.306 a | ||
| Negative | 230 (64.1) | 90 (72) | |
| Positive | 6 (1.7) | 5 (4.0) | |
| Unknown | 123 (34.3) | 30 (24.0) |
EGFR, epidermal growth factor receptor; ALK, anaplastic lymphoma kinase; GGO, ground-glass opacity.
a
The p value was calculated excluded the patients with unknown EGFR and ALK status.