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. 2022 Jan 1;12(2):910–928. doi: 10.7150/thno.66059

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Characterization of cellular composition of human thoracic aorta at single-cell resolution. (A) Schematic of study design. (B) t-distributed stochastic neighbor embedding (t-SNE) clustering of 3,199 cells isolated from human Non-AD or AD aortas. (C) Expression of canonical markers and specific marker in cell clusters. The cell clusters in (B) were identified by the expression of canonical marker genes. (D, E) Gene ontology (GO) analysis of genes specifically expressed in SMCs clusters (D) and FBs clusters (E). Selected top categories are shown.