Table 8.
Representative commercial and non-commercial characteristics of tears-based glucose sensors
| Manufacturer | Type | Sensor material | Configuration | Sensitivity | Linear Range (mg/dL) |
LOD (mg/dL) |
|---|---|---|---|---|---|---|
| Commercial | ||||||
| Roche - ACCU-CHEK Aviva Plus 94,163 | PQQ-GDH | nitrosoaniline-derivative (Mediator) |
Amperometric | 0.127 μAmM-1 | 0.009-2.67 | 0.016 |
| Non-Commercial | ||||||
| Kownacka et al. 164 | GOx | Pt/Ir | Amperometric | - | 1.8-18 | - |
| Kim et al. 165 | Non-enzymatic | Nanoparticle Embedded Contact Lens | Photometric | 0.089Δr'n/mM | 0-44 | - |
| Romeo et al. 166 | Non-enzymatic | PET/Au/CuO/Nafion | Amperometric | 850 μAmM-1 cm-2 | 0.055-12.6 | 0.05 |
PQQ-GDH, pyrroloquinoline quinone dehydrogenase; PET, polyethylene terephthalate; Δr'n, difference of relative reflectance before and after reaction with glucose.