Table 4.
Change in hemodynamic and arterial stiffness parameters after surgery.
| Aortic stenosis | Aortic regurgitation | Ascending aortic dilatation | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| N | Median (IQRs) or mean (SD) | Paired p-value | N | Median (IQRs) or mean (SD) | Paired p-value | N | Median (IQRs) or mean (SD) | Paired p-value | P-value | |
| Δ HR (bpm) | 32 | 14 (8–20) | <0.001 | 27 | 19 (9–32) | <0.001 | 9 | 21 (7–27) | 0.015 | 0.23 |
| Δ SBP (mmHg) | 32 | −2 (21)* | 0.64 | 27 | −17 (24) | 0.001 | 9 | −9 (15) | 0.11 | 0.029 |
| Δ DBP (mmHg) | 32 | −5 (−14 to −1) | 0.001 | 27 | −5 (−12 to 5) | 0.18 | 9 | −9 (−16 to −1) | 0.028 | 0.39 |
| Δ MAP (mmHg) | 32 | −6 (12) | 0.016 | 27 | −8 (14) | 0.009 | 9 | −9 (11) | 0.036 | 0.55 |
| Δ PP (mmHg) | 32 | 3 (−9 to 17)* | 0.14 | 27 | −14 (−31 to 1) | 0.002 | 9 | −4 (−8 to 11) | 0.77 | <0.001 |
| Δ ABI | 32 | −0.04 (−0.11 to 0.04) | 0.074 | 27 | −0.090 (−0.18 to 0.02) | 0.003 | 9 | 0.01 (−0.12 to 0.11) | 0.95 | 0.14 |
| Δ baPWV (m/s) | 30 | 155.3 (−1.4 to 303.7) | <0.001 | 26 | 126.6 (−39.5 to 213.1) | 0.014 | 8 | −83.9 (−228.8 to 232.8) | 0.67 | 0.091 |
| Δ ETc (ms) | 30 | −0.023 (−0.077 to 0.0074)† | <0.001 | 26 | −0.0032 (−0.065 to 0.053) | <0.001 | 8 | 0.051 (−0.0079 to 0.063) | 0.017 | 0.006 |
| Δ B-UT (ms) | 30 | −80 (−108 to −51) | <0.001 | 26 | −59 (−93 to −19) | <0.001 | 8 | −46 (−80 to −20) | 0.012 | 0.077 |
| Δ A-UT (ms) | 30 | −44 (−56 to −33)* | <0.001 | 26 | −18 (−35 to −2) | <0.001 | 8 | −28 (−44 to −13) | 0.012 | <0.001 |
Pairwise comparisons of post-surgery measurement subtracted by baseline measurement (Δ). Data is presented as mean (SD) if normality was proven with Shapiro-Wilk test and absence of outliers. Pairwise comparisons were assessed with paired t-test and Wilcoxon signed rank test as appropriate and comparison of the Δvalue between the three groups was assessed with analysis of variance (ANOVA) or Kruskal-Wallis test as appropriate. HR, heart rate; SBP, systolic blood pressure; DBP, diastolic blood pressure; MAP, mean arterial pressure; ABI, ankle brachial index; baPWV, brachial ankle pulse wave velocity; ETc, heart rate corrected ejection time; B-UT, brachial upstroke time; A-UT, ankle upstroke time.
Indicate Bonferroni adjusted p-value < 0.05 compared with AR-group.
Indicate Bonferroni adjusted p-value < 0.05 compared with AAD-group.