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. 2021 Dec 21;9(12):e003439. doi: 10.1136/jitc-2021-003439

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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Combined analysis of both cohorts. The disappearance of NY-ESO-1-reactive/Melan-A-reactive T cells correlates with prolonged PFS (A) and OS (B). PFS (C) and OS (D) in patients in whom both melanoma-reactive T cell populations were no longer present in the blood (black arm), or in whom just one population disappeared (orange arm), or in whom neither disappeared (red arm). OS, overall survival; PFS, progression-free survival.