Table 1.

Demographics and comorbidities

Parameter	First wave	Second wave	p value
Patients admitted to the ICU (3,498 patients)	1,921	1,577
Gender *
Male	1,412 (73.5%)	1,079 (68.4%)
Female	509 (26.5%)	498 (31.6%)	0.001
Age distribution
Age, n (mean ± SD)	57.6 ± 14.6	56.7 ± 15.5	0.07
<18 years, 9 pts (0.5%)	15 ± 3.24	15 ± 4.27	NS
18–64 years, 2,305 pts (65.89%)	49 ± 10.45	50 ± 10.22	NS
≥65 years, 1,181 pts (33.76%)	73 ± 6.48	73 ± 6	NS
Comorbidity: Yes (No), % with comorbidity*	1,275/1,907 (67%)	1,012/1,388 (73%)	<0.001
Comorbidities
Diabetes mellitus	765/1,898 (40.3%)	586/1,298 (45.1%)	0.007
Hypertension*	848/1,899 (44.7%)	645/1,299 (49.7%)	0.005
Ischemic heart disease*	265/1,890 (14%)	199/1,180 (16.9%)	0.034
Chronic kidney disease*	110/1,890 (5.3%)	105/1,135 (9.8%)	0.001
Malignancy*	38/1,886 (2.0%)	67/1,144 (5.9%)	<0.001
Respiratory disorders*	87/1,884 (4.6%)	119/1,159 (10.3%)	<0.001
Hypothyroidism*	96/1,891 (5.1%)	88/1,146 (7.7%)	0.005

^*Statistically significant