Table 3.
The mRNA expression of related marker genes in jejunal tissues of neonatal piglets in vivo.1
| Item2 | Day after birth |
P-value | |
|---|---|---|---|
| 0 d | 7 d | ||
| Epithelial-specific markers | |||
| Villin | 1.01 ± 0.07 | 0.82 ± 0.06 | 0.089 |
| E-cadherin | 1.02 ± 0.12 | 0.88 ± 0.04 | 0.304 |
| TJP1 | 1.01 ± 0.09 | 0.90 ± 0.08 | 0.379 |
| Differentiation markers | |||
| Alpi | 1.04 ± 0.15 | 0.86 ± 0.05 | 0.311 |
| Muc2 | 1.01 ± 0.10 | 0.94 ± 0.05 | 0.548 |
| Lyz | 1.73 ± 0.78 | 26.51 ± 11.96 | 0.130 |
| ChgA | 1.00 ± 0.03 | 0.83 ± 0.03 | 0.014 |
| Fetal ISC markers | |||
| Tacstd2 | 1.12 ± 0.32 | 1.16 ± 0.15 | 0.903 |
| Gja1 | 1.02 ± 0.11 | 0.83 ± 0.13 | 0.313 |
| Adult ISC markers | |||
| Lgr5 | 1.04 ± 0.18 | 0.99 ± 0.13 | 0.830 |
| Smoc2 | 1.07 ± 0.22 | 2.65 ± 0.47 | 0.022 |
| Cdx1 | 1.03 ± 0.14 | 0.99 ± 0.11 | 0.858 |
1
The values are expressed as mean ± SEM (n = 18). Differences were assessed by the Student's t-test. Values of P < 0.05 are referred to as statistically significant.
2
TJP1 = tight junction protein 1; Alpi = alkaline phosphatase; Muc2 = mucin 2; Lyz = lysozyme; ChgA = chromogranin A; ISC = intestinal stem cells; Tacstd2 = tumor associated calcium signal transducer 2; Gja1 = gap junction protein, alpha 1; Smoc2 = SPARC related modular calcium binding 2; Cdx1 = caudal type homeobox 1; Lgr5 = leucine-rich repeat-containing G protein-coupled receptor 5.