Table 5.
The mRNA expression of genes involved in related signaling pathways in jejunal tissues of neonatal piglets in vivo.1
| Item2 | Day after birth |
P-value | |
|---|---|---|---|
| 0 d | 7 d | ||
| Wnt/β-catenin signaling | |||
| Jag-1 | 1.09 ± 0.24 | 0.42 ± 0.01 | 0.069 |
| Jag-2 | 1.04 ± 0.16 | 0.76 ± 0.08 | 0.177 |
| Sgk1 | 1.17 ± 0.34 | 0.40 ± 0.07 | 0.109 |
| Bmp4 | 1.01 ± 0.08 | 0.72 ± 0.05 | 0.020 |
| Nedd8 | 1.01 ± 0.06 | 0.56 ± 0.01 | 0.004 |
| Ephb4 | 1.02 ± 0.11 | 1.00 ± 0.10 | 0.907 |
| C-Myc | 1.04 ± 0.15 | 1.17 ± 0.20 | 0.598 |
| Ccnd1 | 1.02 ± 0.12 | 0.92 ± 0.08 | 0.486 |
| Axin2 | 1.01 ± 0.07 | 0.71 ± 0.07 | 0.026 |
| EGF signaling | |||
| EGFR | 1.04 ± 0.17 | 1.07 ± 0.11 | 0.885 |
| Notch signaling | |||
| Notch1 | 1.04 ± 0.18 | 0.94 ± 0.13 | 0.683 |
| Notch2 | 1.07 ± 0.21 | 1.07 ± 0.42 | 0.990 |
| Atoch1 | 1.02 ± 0.12 | 1.22 ± 0.14 | 0.326 |
| Hes1 | 1.03 ± 0.15 | 0.91 ± 0.09 | 0.503 |
| Dll1 | 1.04 ± 0.16 | 0.73 ± 0.06 | 0.117 |
| Dll4 | 1.02 ± 0.10 | 1.19 ± 0.11 | 0.279 |
| BMP signaling | |||
| Id1 | 1.06 ± 0.21 | 1.09 ± 0.08 | 0.901 |
| Id2 | 1.03 ± 0.14 | 1.01 ± 0.08 | 0.894 |
| Bmpr1a | 1.04 ± 0.17 | 1.37 ± 0.07 | 0.119 |
| Bmp2 | 1.07 ± 0.22 | 1.34 ± 0.11 | 0.332 |
| Smad4 | 1.03 ± 0.15 | 0.98 ± 0.09 | 0.804 |
The values are expressed as mean ± SEM (n = 18). Differences were assessed by the Student's t-test. Values of P < 0.05 are referred to as statistically significant.
Notch1 = Notch receptor 1; Notch2 = Notch receptor 2; Atoh1 = atonal bHLH transcription factor 1; Hes1 = hes family bHLH transcription factor 1; Dll1 = delta like canonical Notch ligand 1; Dll4 = delta like canonical Notch ligand 4; Jag1 = jagged canonical Notch ligand 1; Jag2 = jagged canonical Notch ligand 2; Sgk1 = serum/glucocorticoid regulated kinase 1; Bmp4 = bone morphogenetic protein 4; Nedd8 = neural precursor cell expressed developmentally down-regulated 8; Ephb4 = EPH receptor B4; Axin2 = axis inhibition protein 2; EGFR = epidermal growth factor receptor; Ccnd1 = cyclin D1; Id1 = inhibitor of DNA binding 1; Id2 = inhibitor of DNA binding 2; Smad4 = SMAD family member 4; Bmp2 = bone morphogenetic protein 2; Bmpr1a = bone morphogenetic protein receptor type 1a.