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. 2021 Dec 5;27:100289. doi: 10.1016/j.jcte.2021.100289

Table 1.

Prevalence of diabetes in CF pregnancy among case series, retrospective cohorts & database reviews.

Reference Study Period, Location & Source # Mothers # Pregnancies % Diabetes (CFRD & GDM) % CFRD % GDM
Gilljam et al. 2000
  • -

    1963–1998

  • -

    CF database

  • -

    Toronto, Canada

 49 74 20%* 6%* 14%*
Edenborough et al. 2000
  • -

    1977 to 1996

  • -

    15 adult CF centers

  • -

    England, Wales & Northern Ireland

 55 69 18%* 14%* 4%*
Odegaard et al. 2002
  • -

    1977 to 1998

  • -

    3 CF Centers

  • -

    Norway & Sweden

 23 33 18% ǂ 6% ǂ 12% ǂ
Barak et al. 2005
  • -

    1977 to 2004

  • -

    CF Registry

  • -

    Israel

 8 11 45% ǂ 18% ǂ 27% ǂ
Cheng et al. 2006
  • -

    1989 to 2004

  • -

    Single large tertiary care center

  • -

    Washington, U.S.A

 25 ‖ 43 62%* 31% * 31%*
McMullen et al. 2006
  • -

    1995 to 2003

  • -

    CF Registry Data

  • -

    U.S.A

 216 – 20.6% ǂ 9.3% ǂ
Lau et al. 2011
  • -

    1995 to 2009

  • -

    1 CF center

  • -

    Australia

 18 20 55%* 22%* 33%*
Thorpe-Beeston et al. 2013
  • -

    1998 to 2011

  • -

    1 CF center

  • -

    U.K.

 41 48 35.4% ǂ – –
Burden et al. 2012
  • -

    2003 to 2011

  • -

    1 CF center

  • -

    U.K.

 12 15 57% ǂ 28.5% ǂ 28.5% ǂ
Jelin et al. 2017*
  • -

    2005–2008

  • -

    Billing ICD-9 codes

  • -

    California, U.S.A

 66 77 15.2%* 4.6%* 10.6%*
Girault et al. 2016
  • -

    2000 to 2013

  • -

    1 CF center

  • -

    France

 29 33 48.5% ǂ 30.3% ǂ 18.2% ǂ
Ashcroft et al. 2020
  • -

    2015 to 2017

  • -

    United Kingdom Obstetric Surveillance System (UKOSS)

  • -

    U.K.

 71 71 66%* 32%* 36%*

* Percentage of mothers with CF diagnosed with and/or treated for diabetes during pregnancy.

ǂ Percentage of pregnancies in women with CF affected by diabetes.

‖ Diabetes status available for 16 of 25 women.