Table 4.

Linkage disequilibrium (LD) analysis in the complete Sporothrix database (n = 173) and within members of the clinical clade.

#3 EcoRI-GA/MseI-TT
LD characteristic	Clinical clade (n = 173)	S. brasiliensis (n = 72)	S. schenckii (n = 67)	S. globosa (n = 34)
Total number of markers	149	100	115	71
Number of markers pairs	11 026	4 950	6 555	2 485
Number of markers pairs at 0 ≤ P ≤ 0.001	1 246 (11.3 %)	114 (2.30 %)	190 (2.89 %)	112 (4.50 %)
Number of markers pairs at 0.001 ≤ P ≤ 0.01	442 (4 %)	132 (2.66 %)	141 (2.15 %)	52 (2.09 %)
Number of markers pairs at r2 = 1	3 (0.02 %)	5 (0.10 %)	14 (0.21 %)	31 (1.24 %)
Mean r2	0.0379	0.0472	0.0436	0.1666
Mean D′	0.6729	0.6931	0.6737	0.7983
#5 EcoRI-GA/MseI-AG
LD characteristic	Clinical clade (n = 173)	S. brasiliensis (n = 72)	S. schenckii (n = 67)	S. globosa (n = 34)
Total number of markers	143	84	110	67
Number of markers pairs	10 153	3 486	5 995	2 211
Number of markers pairs at 0 ≤ P ≤ 0.001	1 067 (10.51 %)	188 (5.39 %)	145 (2.41 %)	22 (0.99 %)
Number of markers pairs at 0.001 ≤ P ≤ 0.01	420 (4.13 %)	134 (3.84 %)	139 (2.31 %)	102 (4.61 %)
Number of markers pairs at r2 = 1	0	8 (0.22 %)	0	43 (1.94 %)
Mean r2	0.0370	0.0697	0.0453	0.1247
Mean D′	0.6299	0.6959	0.6193	0.7527
#6 EcoRI-TA/MseI-AA
LD characteristic	Clinical clade (n = 173)	S. brasiliensis (n = 72)	S. schenckii (n = 67)	S. globosa (n = 34)
Total number of markers	126	75	100	43
Number of markers pairs	7 875	2 775	4 950	903
Number of markers pairs at 0 ≤ P ≤ 0.001	520 (6.60 %)	81 (2.91 %)	54 (1.09 %)	11 (1.21 %)
Number of markers pairs at 0.001 ≤ P ≤ 0.01	298 (3.78 %)	59 (2.12 %)	91 (1.83 %)	22 (2.43 %)
Number of markers pairs at r2 = 1	0	1 (0.03 %)	2 (0.04 %)	15 (1.66 %)
Mean r2	0.0271	0.0543	0.0322	0.1167
Mean D′	0.7111	0.7084	0.6968	0.7505