Table 1.
Engineered lipocalins with novel ligand specificities used for the graphical analysis.
| Ligand specificity | Anticalin | Ligand type | PDB ID |
|---|---|---|---|
| Y-DTPA | Tb7.N9 | Hapten | 3DSZ |
| Y-DTPA | C26 | Hapten | 4IAW |
| Y-DTPA | CL31 | Hapten | 4IAX |
| Catacalin-TSA | C3A5 | Hapten | 6Z2C |
| Colchicine | Δ4-D6.2(M69Q) | Hapten | 5NKN |
| Colchicine (apo) | D6.2 | Hapten | 6Z6Z |
| Petrobactin | Δ4M2 | Hapten | 6GR0 |
| Petrobactin (apo) | Δ4M2 | Hapten | 6GQZ |
| Aβ peptide | H1GA | Peptide | 4MVL |
| Aβ peptide | US7 | Peptide | 4MVI |
| Hepcidin | Ac3 (I24) | Peptide | 4QAE |
| CTLA-4 ectodomain | PRS-010#3 (O10) | Protein | 3BX7 |
| Fn ED-B | N7A | Protein | 4GH7 |
| Fn ED-B | N7E | Protein | 5 N47 |
| Fn ED-B | N9B | Protein | 5 N48 |
| huCD98hcED | P3D11 | Protein | 6S8V |
| muCD98hcED | C1B12 | Protein | 6SUA |
| Wild-type Lcn2 | UniProt ID P80188 | Siderophore | 1L6M |