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. 2021 Jan 5;11(3):1376–1393. doi: 10.1039/d0ra07807g

Magnetic nanoparticles/functionalized magnetic nanoparticles-catalyzed synthesis of 1,4-DHPa.

graphic file with name d0ra07807g-u4.jpg
Entry Catalyst Temperature (°C)/Ultrasonic Probe(W) Solvent Time (min) Yieldb (%) Ref.
1 γ-Fe2O3, MW, and fixed bed flow reactor 100 Solvent free 5 93.5 69
2 γ-Fe2O3@HAp@Melamine 80 Solvent free 15 94 70
3 Fe3O4/SiO2-PDA NPs/USW Room temperature EtOH 10 89 71
4 AIL-SCMNPs 60 Solvent free 10 92 72
5 Ultrasound Fe3O4@SiO2–SnCl4 40 EtOH 5 98 73
6 Fe3O4@SiO2@ADMPT/HPA nano catalyst 70 EtOH 35 92 74
7 NiFe2O4@SiO2–H14NaP5W30O110 120 Solvent free 10 94 75
8 Nano ZnFe2O4 Room temperature H2O 30 90–96 76
9 (a) Hal-Fe3O4 with 1,3-ketoesters Reflux EtOH 20 96 77
(b) Hal-Fe3O4 with dimedone Reflux EtOH 20 94
10 Fe3O4@IG Ultrasound EtOH 50 88 78
11 (a) γ-Fe2O3@Cu@cellulose for 1,4-dihydropyridine derivatives Room temperature Solvent free Completion of reaction 80–92 79
(b) γ-Fe2O3@Cu@cellulose for polyhydroquinoline derivatives Room temperature Solvent free 20 87–95
12 Nano-FGT 100–120 Solvent free 35 80–91 87
13 Fe–C–O–Mo alloy Reflux EtOH 150 92 88
14 Chitosan NPs 80 Solvent free 20 90 89
15 Fe3O4@chitosan Room temperature EtOH 30–140 84–98 90
16 MGCS Reflux EtOH 15 84–89 91
a

Reaction conditions: aldehyde (1.0 mmol), ethyl acetoacetate (2.0 mmol), NH4OAc (1–1.5 mmol), dimedone (2.0 mmol).

b

Isolated yields.